You've probably heard the term by now.
"Food noise." That relentless mental chatter about eating... the negotiating, the craving, the obsessing, the internal loop that plays on repeat no matter how disciplined you think you are, no matter how many diets you've tried, no matter how much willpower you summon.
Recently, I was listening to a conversation between a well-known podcast host and a physician, a former bariatric surgeon, who has become a vocal proponent of GLP-1 medications. What struck me most wasn't his clinical reasoning. It was his personal testimony. He described living with this relentless food noise himself, how no diet, no protocol, no amount of effort ever quieted it... until GLP-1s did.
I want to be clear: I'm not here to take that experience apart. It was honest. It was real. And I understand why it resonates with so many people who have suffered with this for years.
But as someone who has walked the chronic illness journey both as a clinician and as a patient, I found myself asking a different question altogether.
What if food noise isn't a brain chemistry problem waiting to be medicated? What if it's a message from an organ that has been struggling silently for years?
What "Food Noise" Actually Is
Food noise is not a clinical diagnosis. It's a lived experience that millions of people recognize instantly: the constant thoughts about food, the compulsive planning of the next meal, the inability to stop eating when you know you should, the cravings for specific textures and flavors that feel almost wired in. It has historically been framed as a behavioral issue, a willpower deficit, or an emotional eating pattern.
The GLP-1 conversation has begun to shift that narrative toward neuroscience, toward dopamine pathways, reward circuits, satiety signaling in the brain. And that reframe, taking food noise seriously as a physiological experience rather than a moral failing, is genuinely valuable.
But the brain does not operate in isolation. It is in constant conversation with the liver. And that conversation is one that conventional medicine has barely begun to have.
Enter: The Hungry Liver
In his book Liver Rescue, Anthony William writes about something he calls "Mystery Hunger," a phenomenon that I believe holds one of the most important and underappreciated explanations for food noise that we have.
The premise is this: the liver is not simply a detox organ. It is a central metabolic hub that stores glucose and glycogen, the primary fuel source for virtually every system in your body. When those reserves run low, the liver and nervous system communicate distress signals that the body interprets as hunger.
Not appetite. Not emotional craving. Hunger. Real, physiological hunger rooted in the liver's unmet nutritional needs.
As Anthony William writes in Liver Rescue, Chapter 19: "So many people are dealing with low glucose and glycogen reserves, causing our livers and even our nervous systems to go hungry and pass along that hunger to us. When our reserves are low, our heart, kidneys, reproductive system, and spleen are hindered, too, though it's the liver and nervous system that hold the hunger, mostly the liver."
Read that again. The liver holds the hunger. And it passes that hunger on to you.
This is what I want you to sit with for a moment. Because if the liver is nutritionally depleted, burdened by pathogens, excess dietary fat, adrenaline, and the accumulated load of modern life, then the signal it sends is not metaphorical. It is biochemical. And it will not stop until the liver's actual needs are met.
That is not a willpower problem. That is not a reward pathway malfunction. That is a liver asking to be fed.
What Depletes the Liver in the First Place?
Anthony William identifies several key stressors that drain the liver of its glucose and glycogen reserves, contributing directly to this cycle of mystery hunger:
Pathogenic activity. Viral pathogens, including Epstein-Barr virus and others, create a constant burden on the liver, consuming its resources and triggering inflammatory processes that deplete glucose reserves over time.
Excess dietary fat. High-fat diets, even those considered "healthy," can interfere with the liver's ability to absorb and utilize glucose efficiently. This is one reason why fat-heavy protocols can paradoxically intensify cravings over time.
Adrenaline surges. Chronic stress floods the body with adrenaline repeatedly. Anthony William teaches that the liver must absorb and neutralize this adrenaline, and that ongoing exposure is deeply taxing to the liver, compounding its overall burden and contributing to its depletion.
Toxic accumulation. Heavy metals, pesticide residues, and other environmental exposures create a sustained detox burden that the liver carries over years and decades, quietly eroding its functional reserves and its ability to maintain adequate glucose storage.
A Word on GLP-1s
I want to be thoughtful here, because this is not about criticizing anyone's personal choices or dismissing the very real relief some people feel.
But I would be doing you a disservice if I didn't say this plainly: the side effect profile of GLP-1 medications is significant and growing, and the long-term picture is one we simply do not yet fully understand. Muscle loss, gastrointestinal complications, thyroid concerns, and rebound effects upon discontinuation are among the issues being tracked. This is not fearmongering. It is appropriate clinical caution in the face of a very new class of widely prescribed medications.
And perhaps more importantly, quieting the signal does not address what created it.
If food noise is, at least in part, the liver's way of communicating genuine nutritional distress, then suppressing that signal without addressing its root cause is a bit like turning off the fire alarm without putting out the fire.
The liver will continue to be burdened. The viral load will continue to accumulate. The glycogen reserves will continue to run low. And when the medication is reduced or discontinued, the noise will return, because nothing underneath has changed.
You deserve more than symptom management. You deserve to understand what your body has been trying to tell you.
Feeding a Hungry Liver: Where to Begin
Supporting the liver's glucose and glycogen stores is not complicated, but it does require intention. Anthony William identifies what he calls Critical Clean Carbohydrates, specific foods that the liver can actually absorb and use to begin replenishing its reserves. These are not the empty carbohydrates that spike and crash. These are the foods the liver recognizes as nourishment.
Critical Clean Carbohydrates, as Anthony William teaches, include:
Fruit. The liver's most preferred and bioavailable fuel source. Fresh, whole fruit provides glucose in a form the liver can use immediately and efficiently.
Raw honey. A deeply liver-supportive food, raw honey provides a concentrated and highly absorbable form of glucose and fructose that goes directly to work replenishing liver glycogen.
Potatoes and sweet potatoes. Nutrient-dense, grounding, and deeply satisfying, these are among the most underrated healing foods in the pantry. They provide complex glucose that sustains liver reserves over time.
Winter squash. Rich in gentle sugars and minerals that support liver function, winter squash is a powerful and healing Critical Clean Carb, especially in the colder months.
Coconut water. A natural source of electrolytes and glucose that hydrates at a cellular level while providing the liver with readily available fuel.
These Critical Clean Carbohydrates work best when balanced with an abundance of leafy greens and other vegetables, which provide the mineral salts, antioxidants, and phytonutrients the liver needs for its ongoing work.
A few additional foundational supports:
Celery juice. A cornerstone of this work, celery juice helps restore the liver's internal environment, supports its filtration function, and over time creates conditions in which glucose can be better absorbed and utilized.
Reducing the fat burden. Even a temporary reduction in dietary fat can meaningfully shift how well the liver absorbs glucose. This is often one of the most impactful early moves.
Addressing pathogenic load. If there is an underlying viral contributor, and in my clinical experience there very often is, supporting antiviral pathways with targeted foods, herbs, and supplements is part of the deeper work.
Nervous system regulation. Because chronic stress drives ongoing adrenaline release, and the liver bears the burden of absorbing all of that adrenaline, nervous system care is not a luxury. It is a metabolic necessity.
A Different Question
The food noise conversation has opened a door worth walking through. It has moved the discussion away from willpower and shame and toward something physiological. That matters.
But root-cause healing asks us to go one step further. Not just: how do we quiet the noise? But: what has the noise been trying to tell us all along?
In my work, the answer almost always leads back to the liver. To a body that has been carrying too much for too long, signaling its needs in the only language it has.
You deserve a conversation that doesn't just manage your symptoms... but actually understands where they came from.
That is the conversation I am here to have.
With love and clarity,
Dr. Sherri



